The discovery of a prehistoric herbal processing site inside a cave in southern Armenia has reshaped our understanding of early human knowledge, technology, and survival strategies. Radiocarbon dating places the occupation of this cave at approximately 40,000 years ago, during the Upper Paleolithic, a period traditionally ᴀssociated with the emergence of cognitive complexity and symbolic behavior. The excavation—conducted by a collaborative team of archaeologists from the Insтιтute of Archaeology and Ethnography of the National Academy of Sciences of Armenia together with several international insтιтutions—has uncovered what may be one of the earliest known “natural pharmacies” of the Stone Age.

Location and Context of Discovery
The cave, nestled in a limestone ridge overlooking a narrow valley, provides a naturally protected environment ideal for human habitation. Its entrance faces south, allowing sunlight and warmth to penetrate during winter months while remaining cool and dry in summer. The geological stability of the cavity has preserved layers of occupation, charcoal pits, plant residues, stone tools, and fragmented hearth structures. Archaeologists conducting aerial imaging and stratigraphic mapping began noticing unusual concentrations of botanical micro-remains embedded in sediment layers dating to the Upper Paleolithic. This prompted a deeper investigation that ultimately led to the identification of more than 40 species of plants processed and used by prehistoric inhabitants.

Materials, Tools, and Craftsmanship Techniques
Artifacts recovered from the site demonstrate a sophisticated level of botanical processing. Microscopic wear analyses on obsidian blades suggest repeated slicing, grinding, and shredding of fibrous plant materials. Several stone mortars and pestles—fashioned from river cobbles—show residue stains consistent with herbal dyes, aromatic oils, and crushed medicinal roots. Grinding slabs reveal a smooth, glossy sheen, indicating long-term use for pulverizing seeds, leaves, and bark. Some wooden fragments, preserved through mineralization, appear to be remnants of containers or mixing trays, possibly used for storing pigments or poultices.
Phytolith and pollen identification confirm the presence of plants used for food, preservatives, anti-inflammatory treatments, wound care, and even mosquito repellents. Among these are traces of Artemisia (wormwood), Mentha (wild mint), Allium species, and several dye-producing plants rich in tannins. Such botanical diversity shows deliberate selection rather than opportunistic gathering, suggesting deep ecological knowledge and systematic experimentation.

Meaning and Function of the Artifacts
The archaeological evidence points to a multifunctional “herbal laboratory” where early humans prepared substances essential to survival. Medicinal plants likely played a crucial role in treating injuries, infections, and digestive ailments. Colorants extracted from roots and berries may have served ritual purposes, or possibly been used to dye hides and textiles. The presence of insect-repelling herbs indicates careful adaptation to seasonal challenges. Furthermore, the site may have operated as a communal knowledge center, where generation after generation transmitted traditional plant knowledge—an early form of proto-pharmacology long predating organized civilizations.
This discovery not only highlights the ingenuity of prehistoric humans but also challenges modern ᴀssumptions about the technological limitations of early societies. The strategic use of complex botanical mixtures proves that humans of the Upper Paleolithic possessed a refined understanding of chemistry, craft, and the medicinal properties of the natural world.
The Research Team and Excavation Efforts
The ongoing excavation is led by scholars from the Armenian Academy of Sciences along with botanists, paleoethnographers, chemical residue analysts, and international partners specializing in geoarchaeology. Careful documentation—using drones, digital mapping, sediment extraction, and laboratory analysis—has allowed researchers to reconstruct the daily activities within the cave with remarkable detail. Their findings contribute to a growing body of evidence showing that Paleolithic communities across Eurasia practiced plant-based technologies far earlier than previously believed.
The “Stone Age pharmacy” of Armenia stands today as a powerful testament to human innovation, adaptability, and the enduring connection between people and plants. Through this discovery, we gain not only scientific insight but also a deeper respect for our ancestors’ knowledge—knowledge cultivated long before the rise of agriculture, cities, or written records.