The FBI has received important new DNA evidence, including detailed test results from a hair sample collected from the Tucson, Arizona home of Nancy Guthrie, according to multiple sources familiar with the high-profile investigation.

This latest development comes as authorities continue to pursue leads in the mysterious disappearance of the 84-year-old mother of NBC’s “Today” show co-host Savannah Guthrie. Nancy Guthrie was last seen on January 31, 2026, after family members dropped her off following a dinner outing. Hours later, on the early morning of February 1, 2026, disturbing surveillance footage from her Nest doorbell camera captured a masked individual appearing to tamper with the device before the feed went dark. Blood evidence was later discovered on the front porch, raising immediate fears of foul play and an apparent abduction.

A source with direct knowledge of the investigation confirmed that law enforcement recovered various DNA materials — including hair — from inside and around Guthrie’s residence. These samples were promptly shared with the FBI for advanced forensic analysis and testing. The process is expected to provide crucial insights that could help identify potential suspects or clarify the sequence of events on that fateful night.

Renowned investigative genetic genealogist CeCe Moore from Parabon NanoLabs offered expert perspective on the new evidence. She explained that a properly processed hair sample is unlikely to complicate the mixed DNA profiles investigators have previously struggled with. “Not after it is cleaned for contamination,” Moore stated. “They have that process in good shape, but it can take some time.” She further speculated that the hair sample would likely contain DNA from Nancy Guthrie herself, along with contributions from two or more unknown individuals. Authorities had previously indicated that at least one of the DNA contributions in related samples came from a male source.

In addition to the hair analysis, other pieces of evidence have already undergone laboratory processing. Blood found on the front porch has been confirmed to belong to Nancy Guthrie. Investigators also examined a suspicious glove recovered approximately two miles from her home. This glove bore a striking resemblance to those worn by the masked suspect visible in the doorbell camera footage. However, testing revealed no matches in the FBI’s national CODIS database of known offenders, and it did not align with any other DNA samples collected from inside the residence.

The case has captured national attention due to the victim’s connection to Savannah Guthrie and the unsettling circumstances surrounding her vanishing. Despite extensive searches, media appeals, and public tips pouring in, no arrests have been made as of June 2026. The investigation remains active and collaborative between local authorities, including the Pima County Sheriff’s Department, and federal agents.

Both investigators and the Guthrie family have made repeated public appeals for information from anyone who may have seen or heard something suspicious in the area around the time of the disappearance. A substantial reward totaling more than $1.2 million is still being offered — including $1 million from the Guthrie family specifically for information leading to Nancy’s safe recovery. The family has urged the public to contact the FBI directly at 1-800-CALL-FBI with any potential tips or leads.

This new DNA breakthrough from the hair sample represents a hopeful step forward in what has become a complex and emotionally charged case. Forensic experts continue to work diligently behind the scenes, with hopes that advanced genetic analysis will finally provide the answers the family and the public have been desperately seeking. The community in Tucson and beyond remains vigilant as the search for justice and closure continues.